Yes, there are medications that can exacerbate symptoms:

• Antihistamines and tricyclic antidepressants: diminish the force of bladder muscle contraction
• Decongestants (cold remedies): increase the contraction of the muscles that surround the neck of the bladder.
• Diuretics: increase urine production.
• Opiates: interfere with neuro-muscular mechanisms of urination