Knee osteoarthritis

Regeneración de cartílago con células madre cultivadas

The Institute for Tissue Regenerative Therapy (ITRT) has provided scientific evidence proving that it regenerates knee cartilage and is thus indicated for treating elite international athletes and the elderly alike. The therapy naturally creates cartilage where there was none before, with unprecedented results.

Osteoarthritis is a disease that causes progressive degeneration of the joint cartilage structure. It can affect any joint in the body, causing inflammation, pain and deformity to varying degrees.

In many cases, it progresses slowly and does not require treatment, as it can be controlled effectively with medication or physiotherapy; in other cases, it causes pain and significant difficulty when walking, and may even require the implantation of a prosthesis.

The therapy developed by ITRT has been proven in controlled clinical trials using high-resolution magnetic resonance imaging (T2 mapping) to have the ability to regenerate joint cartilage and avoid the need for costly and uncomfortable prostheses.

3

Clinical trials have demonstrated that a single dose of Cultured Mesenchymal Stem Cells is sufficient to unleash regenerative power and heal the injury. The improvement in pain is experienced almost immediately and progresses along with functionality during the first 3 months.

The improvement continues to evolve during the first year and continues over the years, as has been proven in patients treated more than 10 years ago, who have eliminated their injury and regained their lives.

The results have been published in various scientific journals such as Transplantation and The Knee on several occasions.

Clinical trials on osteoarthritis began using the knee joint as a model due to its high prevalence, but once its high effectiveness was demonstrated in clinical trials, the treatment was extended to other joints. During this time, more than 600 patients have been treated for injuries to the hip, ankle, feet, shoulder, elbow, wrist, and hand joints, as the therapeutic concept is the same.

Culture-Based Mesenchymal Stem Cell Therapy

The stem cells that can be extracted from the human body are scarce, insufficient to achieve tissue recovery, so ITRT applied the innovation of multiplying them.

The procedure involves a brief and painless initial intervention in which some stem cells are extracted from the patient's iliac crest (pelvis).

These cells are sent to the laboratory to be cultured under ideal conditions for three weeks, so that they multiply to exceed 250 million units. Millions of cells are extracted from this culture, and the rest of the production is cryogenically frozen and stored in case of future patient needs.

Then, approximately 21 days after the first procedure, the mesenchymal stem cells, once they have been CULTURED, are implanted in the area of the injury.