Tendon injuries

Foto Ensayo Clinico AJSMThe Institute of Tissue Regenerative Therapy (ITRT) is the first centre in the world to have scientifically demonstrated that it can regenerate tendons thanks to its Cultured Mesenchymal Stem Cell (CMSC) therapy. The therapy creates new tissue to leave the injury behind as if it had never existed.

To demonstrate this, a double-blind clinical trial was conducted, comparing two groups of patients, one treated with PRP (Platelet-Rich Plasma) and the other with CMSC. The group treated with PRP showed no improvement, while those treated with CMSC achieved an unprecedented degree of tendon structure regeneration in 100% of patients, with a return to sporting activity after 2 months.

This breakthrough has been recognised by the most prestigious medical journals, including the American Journal of Sports Medicine, which has described it as ‘one of the most significant advances of recent decades’.

What is Tendinopathy?

Tendón Rotuliano Ensayo Clinico AJSM 2

This condition consists of inflammation of the tendon, usually caused by overuse when performing repetitive, high-demand movements, which can lead to a tear

It is common in athletes such as basketball, tennis, football, volleyball, and paddle tennis players, as well as regular runners. It affects both amateurs and elite professionals, among whom it has a prevalence of up to 50%.

Over the past 20 years, ITRT has provided scientific evidence and demonstrated in clinical trials that new tissue can be created in any tendon and the injury can be repaired as if it had never happened. During this time, the centre has treated almost 150 patients for injuries to all tendons, including the patellar, Achilles, hamstring and supraspinatus tendons, among them international elite athletes.

Culture-Based Mesenchymal Stem Cell Therapy

The stem cells that can be extracted from the human body are scarce, insufficient to achieve tissue recovery, so ITRT applied the innovation of multiplying them.

The procedure involves a brief and painless initial intervention in which some stem cells are extracted from the patient's iliac crest (pelvis).

These cells are sent to the laboratory to be cultured under ideal conditions for three weeks, so that they multiply to exceed 250 million units. Millions of cells are extracted from this culture, and the rest of the production is cryogenically frozen and stored in case of future patient needs.

Then, approximately 21 days after the first procedure, the mesenchymal stem cells, once they have been CULTURED, are implanted in the area of the injury.